Monday, December 4
Morning | 9:30 am - 12:30 pm
SC1: Omic Technology for Cancer Immuno-Oncology
Instructors: Somdutta Saha, Ph.D., Post-Doctoral Fellow, Computational Biology, Microbiome, GSK
Lauren Ritterhouse, M.D., Ph.D., Assistant Professor of Pathology, Genomic and Molecular Pathology Division, The University of Chicago Medicine & Biological Sciences
This short course will be an introduction to cover strategies for integrating genomic, proteomic, metabolomic data and more for drug discovery and target validation for cancer immunotherapy. It will introduce current technologies and their limitations.
- Validating novel drug targets or pathways that emerge from human genetics
- Visualization for big data for proteomics
- Targeting the microbiome in I/O
Afternoon | 2:00 - 5:00 pm
SC2: Applications of a Quantitative Imaging Tool Box in Evaluating a CAR Immune Synapse and Contributing to Rational CAR Design
Instructor: Malini Mukherjee, Instructor, Center for Human Immunobiology Cell & Gene Therapy, Baylor College of Medicine
There are many tools that can be utilized to quantitatively measure cell killing. This workshop will outline the following:
- What do we know about the CAR immune synapse?
- What are the tool box components and how do they evaluate a CAR cytotoxic function above and beyond traditional cytotoxicity assays?
- Examples of toolbox based mechanistic understanding of CARs
- Future applications of toolbox in the rational design of CARs
*Separate Registration Required